LabRAM
COS-7 nuclei hosting amastigote forms of Trypanosoma dionisii (Oliveira et al., 2009)
T. cruzi amastigote in the cytoplasm of a HeLa cell (Mortara et al., 2008)
T. cruzi amastigotes in Vero cells labeled with Mab 4B5 - Honorable Mention on the 2005 Olympus BioScapes Digital Imaging Competition
T. cruzi extracellular amastigote and trypomastigote invading HeLa cells ( Fernandes et al., 2011 & 2013)
Trypanosoma cruzi trypomastigotes induce cytoskeleton modifications during HeLa cell invasion (Fernandes, Andrade et al., 2011)
Possibly the first DIC image acquired through a confocal microscope, MRC-500 (Brad Amos, personal communication).
Trypanosoma cruzi metacyclic trypomastigotes invading HeLa cells: DIC image on the left and 3F5 anti-Mucin Mab on the right
(Florentino, Real et al. 2014)
Trypanosoma cruzi amastigotes amongst HeLa cell cytoskeletal fibers and a trypomastigote nest within infected heart mouse muscle (Florentino, Real et al., 2014)
Live Trypanosoma cruzi amastigotes in intestine (Ferreira et al., 2016) and macrophage vacuole coinfected with T. cruzi and Leishmania amazonensis (Pessoa et al., 2016)
Trypanosoma cruzi trypomastigotes egressing from an infected cell (Florentino et al. 2014)
Cardiomyocyte infected with Trypanosoma cruzi (actin in red, T. cruzi in green and nuclei and kinetoplasts in blue)
Alexis Bonfim-Melo: winner of the First prize - 2017 CNPq award for Photography and Art (Link)
Vero cell infected with Trypanosoma cruzi amastigotes, lysed in the presence of taxol and phalloidin. Éden Ferreira, mBio 2021
Renato A. Mortara: personal information
email: ramortara@unifesp.br
BA: Pharmacy, Faculdade de Ciências Farmacêuticas da Universidade de São Paulo, 1977.
MSc: Biochemistry, Instituto de Química, Universidade de São Paulo, 1980. Thesis: "Formation and properties of vesicles made from synthetic phospholipids". Supervisor: Dr. Hernan Chaimovich.
PhD: University of Cambridge (King's College) and MRC Laboratory of Molecular Biology, Inglaterra, 1986. Tese: "Microfilament- membrane interactions in isolated P815 filopodia". Supervisor: Dr. Gordon L.E. Koch.
Full-Lectureship (Livre Docência): Disciplina de Parasitologia, Departamento de Micro, Imuno e Parasitologia, Escola Paulista de Medicina, UNIFESP, 2002. Thesis: "Membrane projections: from retroviruses and bacteria to Trypanosoma cruzi: microorganisms that subvert the host cell".
50th birthday celebration !!
CURRENT POSITION
Full Professor, Division of Parasitology, Departamento de Microbiologia, Imunologia e Parasitologia, Escola Paulista de Medicina - UNIFESP
Rua Botucatu, 862 6º andar, 04023-062, São Paulo SP.
JOURNAL COVERS and other images
UNDERGRADUATE LECTURES: PARASITOLOGY: Nursing School, Biomedical Sciences and Medicine.
REGULAR COURSES FOR THE GRADUATE PROGRAMME IN MICROBIOLOGY and IMMUNOLOGY - UNIFESP (home page)
Tópicos em Biologia Celular (Topics in Cell Biology)
Microscopia Confocal Básica (Basics on Confocal Microscopy)
RESEARCH LINES
Cell biology of Trypanosoma cruzi focussing on invasion and intracellular trafficking of different infective forms of the parastite, particularly extracellular amastigotes. Cell egress.
Coinfections. Leishmania amazonensis: biogenesis of parasitophorous vacuole. Coxiella burnetii: infection and coinfection with other pathogens.
See also: link to SelectScience on Brazil Special Editorial Feature video released on October, 2013 here
See also: Microdevices to study parasite motility and migration: great fun ! here
See also: link to SelectScience on Brazil Special Editorial Feature video released on October, 2013 here
Pluricell cardiomyocytes infected with GFP-Trypanosoma cruzi